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Dr Alasdair Nisbet

Niche-specific gene expression in Teladorsagia circumcincta

Alasdair Nisbet

 +44 (0)131 445 5111

Bush Loan
EH26 0PZ


My research interests relate to the exploration and design of novel methods for controlling pests and parasites particularly through exploiting their unique physiology and their interactions with the host. I am head of the Vaccines Pillar at Moredun Research Institute and also part of EPIC, the Scottish Centre of Expertise on animal disease outbreaks.  Follow the links to find out more information about all of my research interests, activities and publications.

For SEFARI I have contributed to the developed of a prototype vaccine exploiting multiple key proteins derived from Teladorsagia circumcincta - one of five roundworms commonly found in sheep in the UK and the most economically-important to control against currently. This prototype vaccine provides the highest levels of protection in the definitive host for its type.

My ongoing work focuses on developing a more simplified prototype vaccine and to establish whether it has equivalent or enhanced ability to control Teladorsagia circumcincta in young lambs and whether the response in older animals can be optimised further. This work complements projects in which I am currently involved funded by the EU (Paragone) and BBRSC Animal Health and Research Club.


Research Papers (DOI)

Leading Ideas

  • Livestock Diseases
  • Livestock Health

Area of Strategic Research Programme

Further information the Scottish Government's Strategic Research Programme is available

  • Theme 2: Productive and sustainable land management and Rural Economies
  • 2.2 - Livestock Production, Health, Welfare, and Disease Control
  • 2.2.3 Disease mechanisms
  • 2.2.5 Novel vaccines