Our annual Spotlight reports illustrate how our research is leading ideas within Scotland, the UK and globally. SEFARI, in collaboration with Scotland’s Centre of Expertise in Water (CREW), sponsors collaborative projects on Scotland’s water quality, water supply and the influence of climate change. The latest report focuses upon our water-related research and provides summaries of some of these projects ranging across topics such as sustaining cool river temperatures, restoration activities within the River Dee catchment area, new approaches to detect sources of river sediments, measuring emerging river contaminants, and the waterborne transmission of the parasite Toxoplasma gondi. Our Spotlight reports provide an annual snapshot of our extensive range of policy, practice and innovation impacts. Amongst the research covered in this edition are examples related, but not limited to, safeguarding plant and animal health, making Scotland’s food and drink sector more resilient, improving human health and nutrition, and protecting Scotland’s vital natural resources. You can also read Spotlights for the years 2011-2012, 2012-2013, 2013-2014, 2015-2016, 2016-2017 and 2017-2018. Our research is made possible by mid to long-term investment in areas of research which are challenging, complex, and yet have the potential to result in major benefits for Scotland, UK and globally. The economic benefits of the of the previous five year (2011-2016) strategic research programme have been estimated in a recent impact assessment. SEFARI is demonstrably delivering both direct and indirect benefits; but it is likely that the real impact from these examples will manifest considerably beyond this funding cycle.